Journal: International journal of obesity (2005)

Article Title: Maternal high fat diet reversal improves placental hemodynamics in a nonhuman primate model of diet-induced obesity

doi: 10.1038/s41366-018-0145-7

Figure Lengend Snippet: A. Schematic representation of the study design indicating data collection time points with the proportion of gestation (0.5, 0.7 and 0.75) given in parentheses. B. Body weight in all groups at preconception through the third trimester. C. Body weight in the diet reversal group at preconception (0=initiation of diet intervention), 3 months after dietary intervention, and third trimester (G130). D. Fat-to-lean mass ratio determined by dual-energy X-ray absorptiometry scan pre- and post-pregnancy. E. Cholesterol levels, F. Low density lipoprotein levels, and G. Triglyceride levels at G120. Data are presented as the mean ± standard error of the mean for each diet group (CON, n=6; WSD, n=6; REV, n=5). a p<0.001 REV vs . CON; b p<0.01 REV vs . CON, Kruskal-Wallis test; c p<0.013 months vs .0 months, Friedman test; d p<0.05 REV vs . CON; e p=0.007 WSD vs . CON, Kruskal-Wallis test. G, gestational day; CON, control; WSD, Western-style diet; REV, diet reversal; trim, trimester; LDL, low density lipoprotein.

Article Snippet: Body composition for each animal was determined by dual-energy X-ray absorptiometry (DEXA) scans (Hologic QDR Discovery A; Hologic, Inc., Bedford, MA, USA) prior to pregnancy and in the postpartum period.

Techniques: Control, Western Blot

Journal: Reproductive Sciences

Article Title: Adverse Placental Perfusion and Pregnancy Outcomes in a New Nonhuman Primate Model of Gestational Protein Restriction

doi: 10.1177/1933719117704907

Figure Lengend Snippet: Study design overview. Timeline of the experimental design indicating the dietary switch prior to the natural breeding season and the study time points. Maternal metabolic measurements (DEXA and ivGTT) and imaging studies consisting of ultrasound, amniocentesis, and blood sampling are indicated. Animals were allowed to deliver naturally at term and offspring were followed postnatally until 7 months of age. DEXA indicates dual-energy X-ray absorptiometry; G, gestational day; ivGTT, intravenous glucose tolerance tests; P, postnatal day.

Article Snippet: Total body fat for each animal was determined by conducting dual-energy X-ray absorptiometry (DEXA) scans (Hologic QDR Discovery A; Hologic, Inc, Bedford, Massachusetts).

Techniques: Imaging, Sampling

Journal: Reproductive Sciences

Article Title: Adverse Placental Perfusion and Pregnancy Outcomes in a New Nonhuman Primate Model of Gestational Protein Restriction

doi: 10.1177/1933719117704907

Figure Lengend Snippet: Maternal phenotype. A, Maternal body weight at 4 time points: prior to diet switch (pre-diet), post-diet switch, preconception (pre-preg), and at G85 and G135; (B) DEXA data demonstrating lean mass in (a) CON and (b) PR and fat mass in (c) CON and (d) PR animals prior to dietary switch (baseline) and 30 days postinfant delivery (P30). Fasting glucose (C), fasting insulin (D), and C-peptide levels (E) in CON and PR animals prepregnancy (baseline) and in the early third trimester (G120). Data are mean + SEM. *P < .05 third trimester versus baseline, **P < .01 P30 versus baseline, by 2-way ANOVA with Sidak post hoc test. ANOVA indicates analysis of variance; DEXA dual-energy X-ray absorptiometry; PR, protein restriction; SEM, standard error of the mean.

Article Snippet: Total body fat for each animal was determined by conducting dual-energy X-ray absorptiometry (DEXA) scans (Hologic QDR Discovery A; Hologic, Inc, Bedford, Massachusetts).

Techniques: